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Why is the T-cell Immunoreceptor with Ig and ITIM Domains (TIGIT) Pathway a Promising Cancer Treatment Target?

FACULTY

Diwakar Davar, MD
UPMC Hillman Cancer Center
Assistant Professor of Medicine
University of Pittsburgh School of Medicine
Pittsburgh, PA

PROGRAM OVERVIEW

This enduring activity will focus on the T-cell Immunoreceptor with Ig and ITIM Domains (TIGIT).

TARGET AUDIENCE

This activity is intended for U.S.-based oncologists, nurse practitioners, physician assistants, nurses, pharmacists, and other members of oncology multidisciplinary teams involved in the management of patients with advanced solid tumors.

LEARNING OBJECTIVES

  • Evaluate the immunomodulatory activity of TIGIT in anti-cancer immunity
  • Assess the anti-tumor effects of dual blockade of TIGIT and ICIs
  • Interpret evidence from clinical trials assessing the efficacy, safety, and tolerability of emerging TIGIT inhibitor–ICI combinations with different mechanisms of action for the treatment of patients with advanced solid tumors

ACCREDITATION STATEMENT

Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

This CME activity was planned and produced in accordance with the ACCME Essentials.

CREDIT DESIGNATION STATEMENT

Med Learning Group designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the enduring activity.

NURSING CREDIT INFORMATION

Purpose: This program would be beneficial for nurses involved in the care of people with solid tumors.
CNE Credits: 1.0 ANCC Contact Hour.

CNE ACCREDITATION STATEMENT

Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Awarded 1.0 contact hour of continuing nursing education of RNs and APNs.

DISCLOSURE POLICY STATEMENT

In accordance with the Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support, educational programs sponsored by Med Learning Group must demonstrate balance, independence, objectivity, and scientific rigor. All faculty, authors, editors, staff, and planning committee members participating in an MLG-sponsored activity are required to disclose any relevant financial interest or other relationship with the manufacturers of any commercial products and/or providers of commercial services that are discussed in an educational activity.

DISCLOSURE OF CONFLICTS OF INTEREST

Dr. Davar receives institutional research support from Arcus, BMS, Merck, Checkmate Pharmaceuticals, CellSight Technologies, Immunocore, and Tesaro/GSK and is a consultant for Checkmate Pharmaceuticals, Finch, Shionogi, and Vedanta Biosciences.

He also holds two patents related to cancer treatment

CME Content Review

The content of this activity was independently peer-reviewed.
The reviewer of this activity has nothing to disclose.

CNE Content Review

The content of this activity was peer-reviewed by a nurse reviewer.

Douglas Cox, MSN, MHA, RN
Ultimate Medical Academy/CCM – Lead Nurse Planner

The reviewer of this activity has nothing to disclose.

Staff Planners and Managers

The staff, planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CE activity:

Matthew Frese, General Manager of Med Learning Group, has nothing to disclose.
Christina Gallo, SVP, Educational Development of Med Learning Group, has nothing to disclose.
Debra Gordon, Medical Director of Med Learning Group, has nothing to disclose.
Douglas Cox, MSN, MHA, RN, UMA/CCM – LNP, has nothing to disclose.
Lauren Welch, MA, VP of Accreditation and Outcomes of Med Learning Group, has nothing to disclose.
Daniel Dasilva, Accreditation and Outcomes Coordinator of Med Learning Group has nothing to disclose.
Felecia Beachum, Program Manager of Med Learning Group, has nothing to disclose.
Naomi De Brito, Program Coordinator of Med Learning Group has nothing to disclose.

DISCLOSURE OF UNLABELED USE

Med Learning Group requires that faculty participating in any CME activity disclose to the audience when discussing any unlabeled or investigational use of any commercial product or device not yet approved for use in the United States.

During this lecture, faculty may mention the use of medications for both FDA-approved and non-approved indications.

METHOD OF PARTICIPATION

There are no fees for participating and receiving CME credit for this enduring activity. To receive CME/CNE credit participants must:

  1. Read the CME/CNE information and faculty disclosures
  2. Participate in the enduring activity
  3. Submit the evaluation form to Med Learning Group

You will receive your certificate on completion.

DISCLAIMER

Med Learning Group makes every effort to develop CME activities that are science-based. This activity is designed for educational purposes. Participants have a responsibility to use this information to enhance their professional development in an effort to improve patient outcomes. Conclusions drawn by the participants should be derived from careful consideration of all available scientific information. The participant should use his/her clinical judgment, knowledge, experience, and diagnostic decision-making before applying any information, whether provided here or by others, for any professional use.

For CME questions, please contact Med Learning Group at info@medlearninggroup.com

Contact this CME provider at Med Learning Group for privacy and confidentiality policy statement information at http://medlearninggroup.com/privacy-policy/

AMERICANS WITH DISABILITIES ACT

Staff will be glad to assist you with any special needs. Please contact Med Learning Group prior to participating at info@medlearninggroup.com

 

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